The continuing mission of the Kalbasi Lab is to explore the intricate connections between cancer and the immune system, seeking out new biology and therapeutic insights. Our focus lies in exploring the dynamics of the cancer-immune interface within specific disease and therapeutic contexts:
Our Approach
We employ cutting-edge gene editing and synthetic biology techniques to manipulate cells at the cancer-immune interface, using models that faithfully mimic the complexities of cancer and the immune system.
We track these manipulations by combining classical immunological methods with integrated multi-omic strategies. To validate the clinical significance of our findings, we study samples graciously contributed by patients.